Biomedical Research Institute

Schistosomiasis Resource Center Reagents

The Schistosomiasis Resource Center was established by the Biomedical Research Institute, Rockville, Maryland in 1995. For a comprehensive list of schistosomiasis-related reagents available from the SRC, write to Margaret Mentink-Kane, Ph.D.

SNAILS

  • Unexposed (naïve) Biomphalaria glabrata (NMRI, M-line and BS-90 strains)
  • Unexposed (naïve) Bulinus truncatus truncatus (Egyptian strain)
  • Unexposed (naïve) Bulinus wrighti (Oman)
  • Unexposed (naïve) Oncomelania hupensis hupensis (Chinese strain)
  • Unexposed (naïve) Oncomelania hupensis quadrasi (Philippine strain)
3snailsclass - Biomedical Research Institute

PARASITES

S. haematobium

  • S. haematobium (Egyptian) – exposed Bulinus truncatus truncatus
  • S. haematobium (Egyptian) – exposed LVG Golden Syrian hamsters

S. japonicum

  • S. japonicum (Philippine) – exposed Oncomelania hupensis quadrasi
  • S. japonicum (Chinese) – exposed Oncomelania hupensis subsp.
  • S. japonicum (Philippine or Chinese strain) – exposed mice

S. mansoni lines

  • Schistosoma mansoni Praziquantel Extreme Resistant (SmPZQ-ER) – exposed B. glabrata
  • Schistosoma mansoni Praziquantel Extreme Resistant (SmPZQ-ER) – exposed mice or hamsters
  • Schistosoma mansoni Praziquantel Extreme Sensitive (SmPZQ-ES) – exposed B. glabrata
  • Schistosoma mansoni Praziquantel Extreme Sensitive (SmPZQ-ES) – exposed mice or hamsters
  • Schistosoma mansoni Oxamniquine Resistant (SmOR) – exposed B. glabrata
  • Schistosoma mansoni Oxamniquine Resistant (SmOR) – exposed mice or hamsters

S. mansoni

  • S. mansoni (Cairo Egypt) – exposed Biomphalaria alexandrina
  • S. mansoni (NMRI) – exposed B. glabrata (NMRI)
  • S. mansoni (NMRI) – exposed mice or hamsters
  • S. mansoni (PR-1) – exposed B. glabrata (M line)
  • S. mansoni (PR-1) – exposed mice or hamsters

MOLLUSCAN CELL LINE

MOLECULAR REAGENTS

  • Genetic material from various stages of parasites or snail hosts (genomic DNA, cDNA, total RNA, polyA RNA, mRNA)
  • Full length cDNA libraries form susceptible and resistant snails
  • Specific gene constructs from schistosome stages
  • Primers for S. mansoni and B. glabrata

Schistosomiasis Reagents

In addition to fostering the development of schistosomiasis research, the SRC offers technical assistance to other laboratories on snail propagation and maintenance, parasite collection and animal infection protocols.

To order reagents from the Schistosomiasis Resource Center, please contact the SRC at mmentinkkane@afbr-bri.org,